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MiRXES CoVClear Mutation Panel

MiRXES CoVClear SARS-CoV-2 變異株偵測套組

產品說明
MiRXES CoVClear Mutation Panel 是利用RT-qPCR 技術，用於定性檢測 SARS-CoV-2 病毒的Spike蛋白受體結合域 (RBD) 中的兩種關鍵突變（E484K 和 L452R）。
功能說明
原理: 
Mutation Panel共分三組Assay，分別可以檢測CoVID-19病毒SPIKE protein上的第484號及第452號位置的氨基酸是否有產生變異。此套kit可用於定序前先篩選出具有變異的病毒株後再進行定序，大幅提升定序的效率。
WHO Label Pango Lineage First identified Mutation Panel Targets Other spike protein substitutions
Delta B.1.617.2 India L452R D614G, P681R
Beta B.1.351 South Africa E484K D80A, D215G, 241/243del, K417N, N501Y, D614G, A701V
Gamma P.1 Brazil E484K L18F, T20N, P26S, D138Y, R190S, K417T, N501Y, D614G, H655Y, T1027I, V1176F
Eta B.1.525 Multiple countries E484K Q52R, A67V, 69/70del, 144del, D614G, Q677H, F888L
Epsilon B.1.427/B.1.429 USA, California L452R S13I, W152C, D614G
Mu B.1.621 Colombia E484K N501Y, P681H
*WHO-designated variants of concern (VOCs) and selected variants of interest (VOIs), as of 29 November 2021.
 
規格說明
Product Pack Size Contents Catalogue No.
CoVClear Mutation Panel Reagent Pack 200 tests/kit Reaction Master Mix, Enzyme Mix, Positive Control (WT+N), Negative Control FGS0032R
CoVClear Mutation Panel E484K 200 tests/kit Primer-Probe Mix (E484K+N), Positive Control (E484K+N) FGS0035R
CoVClear Mutation Panel L452R 200 tests/kit Primer-Probe Mix (L452R+N), Positive Control (L452+N) FGS0036R
 
 
 
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